A Dual Role of erbB2 in Myelination and in Expansion of the Schwann Cell Precursor Pool

Neuregulin-1 provides an important axonally derived signal for the survival and growth of developing Schwann cells, which is transmitted by the ErbB2/ErbB3 receptor tyrosine kinases. Null mutations of the neuregulin-1, erbB2, or erbB3 mouse genes cause severe deficits in early Schwann cell developme...

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Detalles Bibliográficos
Autores principales: Garratt, Alistair N., Voiculescu, Octavian, Topilko, Piotr, Charnay, Patrick, Birchmeier, Carmen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174554/
https://www.ncbi.nlm.nih.gov/pubmed/10704452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174554/
https://www.ncbi.nlm.nih.gov/pubmed/10704452

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