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Systems metabolic engineering of Escherichia coli for L-threonine production

Amino-acid producers have traditionally been developed by repeated random mutagenesis owing to the difficulty in rationally engineering the complex and highly regulated metabolic network. Here, we report the development of the genetically defined L-threonine overproducing Escherichia coli strain by...

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Detalles Bibliográficos
Autores principales: Lee, Kwang Ho, Park, Jin Hwan, Kim, Tae Yong, Kim, Hyun Uk, Lee, Sang Yup
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174629/
https://www.ncbi.nlm.nih.gov/pubmed/18059444
http://dx.doi.org/10.1038/msb4100196