Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response

We examined responses of the B-cell antigen receptor-dependent intracellular signaling network to targeted perturbations induced through siRNA-mediated depletion of select signaling intermediates. The constituent nodes displayed graded sensitivities, which resulted from the differential effects of p...

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Detalles Bibliográficos
Autores principales: Kumar, Dhiraj, Srikanth, Ravichandran, Ahlfors, Helena, Lahesmaa, Riitta, Rao, Kanury V S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174630/
https://www.ncbi.nlm.nih.gov/pubmed/18059445
http://dx.doi.org/10.1038/msb4100197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174630/
https://www.ncbi.nlm.nih.gov/pubmed/18059445
http://dx.doi.org/10.1038/msb4100197

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