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Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response
We examined responses of the B-cell antigen receptor-dependent intracellular signaling network to targeted perturbations induced through siRNA-mediated depletion of select signaling intermediates. The constituent nodes displayed graded sensitivities, which resulted from the differential effects of p...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174630/ https://www.ncbi.nlm.nih.gov/pubmed/18059445 http://dx.doi.org/10.1038/msb4100197 |