Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase

BACKGROUND: Efficient and correct repair of DNA damage, especially DNA double-strand breaks, is critical for cellular survival. Defects in the DNA repair may lead to cell death or genomic instability and development of cancer. Non-homologous end-joining (NHEJ) is the major repair pathway for DNA dou...

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Detalles Bibliográficos
Autores principales: Karlsson, Karin H, Stenerlöw, Bo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174948/
https://www.ncbi.nlm.nih.gov/pubmed/17963495
http://dx.doi.org/10.1186/1471-2199-8-97

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174948/
https://www.ncbi.nlm.nih.gov/pubmed/17963495
http://dx.doi.org/10.1186/1471-2199-8-97

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