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Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase
BACKGROUND: Efficient and correct repair of DNA damage, especially DNA double-strand breaks, is critical for cellular survival. Defects in the DNA repair may lead to cell death or genomic instability and development of cancer. Non-homologous end-joining (NHEJ) is the major repair pathway for DNA dou...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174948/ https://www.ncbi.nlm.nih.gov/pubmed/17963495 http://dx.doi.org/10.1186/1471-2199-8-97 |