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Evolutionary conservation of P-selectin glycoprotein ligand-1 primary structure and function

BACKGROUND: P-selectin glycoprotein ligand-1 (PSGL-1) plays a critical role in recruiting leukocytes in inflammatory lesions by mediating leukocyte rolling on selectins. Core-2 O-glycosylation of a N-terminal threonine and sulfation of at least one tyrosine residue of PSGL-1 are required for L- and...

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Detalles Bibliográficos
Autores principales: Baïsse, Bénédicte, Galisson, Frédérique, Giraud, Sylvain, Schapira, Marc, Spertini, Olivier
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174952/
https://www.ncbi.nlm.nih.gov/pubmed/17868453
http://dx.doi.org/10.1186/1471-2148-7-166