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Enhancing Exposure of HIV-1 Neutralization Epitopes through Mutations in gp41
BACKGROUND: The generation of broadly neutralizing antibodies is a priority in the design of vaccines against HIV-1. Unfortunately, most antibodies to HIV-1 are narrow in their specificity, and a basic understanding of how to develop antibodies with broad neutralizing activity is needed. Designing m...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174964/ https://www.ncbi.nlm.nih.gov/pubmed/18177204 http://dx.doi.org/10.1371/journal.pmed.0050009 |