Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level

Human α-Synuclein (αSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential importance...

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Detalles Bibliográficos
Autores principales: Sandal, Massimo, Valle, Francesco, Tessari, Isabella, Mammi, Stefano, Bergantino, Elisabetta, Musiani, Francesco, Brucale, Marco, Bubacco, Luigi, Samorì, Bruno
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174973/
https://www.ncbi.nlm.nih.gov/pubmed/18198943
http://dx.doi.org/10.1371/journal.pbio.0060006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174973/
https://www.ncbi.nlm.nih.gov/pubmed/18198943
http://dx.doi.org/10.1371/journal.pbio.0060006

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