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Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
Human α-Synuclein (αSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential importance...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174973/ https://www.ncbi.nlm.nih.gov/pubmed/18198943 http://dx.doi.org/10.1371/journal.pbio.0060006 |