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Noise Propagation and Signaling Sensitivity in Biological Networks: A Role for Positive Feedback

Interactions between genes and proteins are crucial for efficient processing of internal or external signals, but this connectivity also amplifies stochastic fluctuations by propagating noise between components. Linear (unbranched) cascades were shown to exhibit an interplay between the sensitivity...

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Detalles Bibliográficos
Autores principales: Hornung, Gil, Barkai, Naama
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174979/
https://www.ncbi.nlm.nih.gov/pubmed/18179281
http://dx.doi.org/10.1371/journal.pcbi.0040008