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Integrin-Mediated Survival Signals Regulate the Apoptotic Function of Bax through Its Conformation and Subcellular Localization

Most normal cells require adhesion to extracellular matrix for survival, but the molecular mechanisms that link cell surface adhesion events to the intracellular apoptotic machinery are not understood. Bcl-2 family proteins regulate apoptosis induced by a variety of cellular insults through acting o...

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Detalles Bibliográficos
Autores principales: Gilmore, Andrew P., Metcalfe, Anthony D., Romer, Lewis H., Streuli, Charles H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175159/
https://www.ncbi.nlm.nih.gov/pubmed/10769034