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P21 and Retinoblastoma Protein Control the Absence of DNA Replication in Terminally Differentiated Muscle Cells

During differentiation, skeletal muscle cells withdraw from the cell cycle and fuse into multinucleated myotubes. Unlike quiescent cells, however, these cells cannot be induced to reenter S phase by means of growth factor stimulation. The studies reported here document that both the retinoblastoma p...

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Detalles Bibliográficos
Autores principales: Mal, Asoke, Chattopadhyay, Debasis, Ghosh, Mrinal K., Poon, Randy Y.C., Hunter, Tony, Harter, Marian L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175169/
https://www.ncbi.nlm.nih.gov/pubmed/10769022