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Nicotinic Acid Adenine Dinucleotide Phosphate (Naadp(+)) Is an Essential Regulator of T-Lymphocyte Ca(2+)-Signaling

Microinjection of human Jurkat T-lymphocytes with nicotinic acid adenine dinucleotide phosphate (NAADP(+)) dose-dependently stimulated intracellular Ca(2+)-signaling. At a concentration of 10 nM NAADP(+) evoked repetitive and long-lasting Ca(2+)-oscillations of low amplitude, whereas at 50 and 100 n...

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Detalles Bibliográficos
Autores principales: Berg, Ingeborg, Potter, Barry V.L., Mayr, Georg W., Guse, Andreas H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175191/
https://www.ncbi.nlm.nih.gov/pubmed/10931869