Fission Yeast Bub1 Is a Mitotic Centromere Protein Essential for the Spindle Checkpoint and the Preservation of Correct Ploidy through Mitosis

The spindle checkpoint ensures proper chromosome segregation by delaying anaphase until all chromosomes are correctly attached to the mitotic spindle. We investigated the role of the fission yeast bub1 gene in spindle checkpoint function and in unperturbed mitoses. We find that bub1 (+) is essential...

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Detalles Bibliográficos
Autores principales: Bernard, Pascal, Hardwick, Kevin, Javerzat, Jean-Paul
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175213/
https://www.ncbi.nlm.nih.gov/pubmed/9864354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175213/
https://www.ncbi.nlm.nih.gov/pubmed/9864354

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