Conditional Ablation of β1 Integrin in Skin: Severe Defects in Epidermal Proliferation, Basement Membrane Formation, and Hair Follicle Invagination

The major epidermal integrins are α3β1 and hemidesmosome-specific α6β4; both share laminin 5 as ligand. Keratinocyte culture studies implicate both integrins in adhesion, proliferation, and stem cell maintenance and suggest unique roles for αβ1 integrins in migration and terminal differentiation. In...

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Detalles Bibliográficos
Autores principales: Raghavan, Srikala, Bauer, Christoph, Mundschau, Gina, Li, Qingqin, Fuchs, Elaine
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175239/
https://www.ncbi.nlm.nih.gov/pubmed/10974002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175239/
https://www.ncbi.nlm.nih.gov/pubmed/10974002

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