Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release

Proapoptotic members of the Bcl-2 protein family, including Bid and Bax, can activate apoptosis by directly interacting with mitochondria to cause cytochrome c translocation from the intermembrane space into the cytoplasm, thereby triggering Apaf-1–mediated caspase activation. Under some circumstanc...

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Detalles Bibliográficos
Autores principales: von Ahsen, Oliver, Renken, Christian, Perkins, Guy, Kluck, Ruth M., Bossy-Wetzel, Ella, Newmeyer, Donald D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175243/
https://www.ncbi.nlm.nih.gov/pubmed/10973993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175243/
https://www.ncbi.nlm.nih.gov/pubmed/10973993

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