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p53-dependent stimulation of redox-related genes in the lymphoid organs of γ-irradiated mice—identification of Haeme-oxygenase 1 as a direct p53 target gene

Recent data showed that p53 stimulates the expression of genes encoding not only pro- but also antioxidant enzymes. It was suggested that antioxidant genes could be induced under physiologic levels of stress while the prooxidant ones respond to higher level of stress. Results presented in this artic...

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Detalles Bibliográficos
Autores principales: Meiller, Anne, Alvarez, Sandra, Drané, Pascal, Lallemand, Christophe, Blanchard, Brigitte, Tovey, Micheal, May, Evelyne
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175302/
https://www.ncbi.nlm.nih.gov/pubmed/17933770
http://dx.doi.org/10.1093/nar/gkm824