Modeling DNA-binding of Escherichia coli σ(70) exhibits a characteristic energy landscape around strong promoters

We present a computational model of DNA-binding by σ(70) in Escherichia coli which allows us to extract the functional characteristics of the wider promoter environment. Our model is based on a measure for the binding energy of σ(70) to the DNA, which is derived from promoter strength data and used...

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Detalles Bibliográficos
Autores principales: Weindl, Johanna, Hanus, Pavol, Dawy, Zaher, Zech, Juergen, Hagenauer, Joachim, Mueller, Jakob C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175306/
https://www.ncbi.nlm.nih.gov/pubmed/17940097
http://dx.doi.org/10.1093/nar/gkm720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175306/
https://www.ncbi.nlm.nih.gov/pubmed/17940097
http://dx.doi.org/10.1093/nar/gkm720

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