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Site-specific interaction of the murine pre-replicative complex with origin DNA: assembly and disassembly during cell cycle transit and differentiation

Eukaryotic DNA replication initiates at origins of replication by the assembly of the highly conserved pre-replicative complex (pre-RC). However, exact sequences for pre-RC binding still remain unknown. By chromatin immunoprecipitation we identified in vivo a pre-RC-binding site within the origin of...

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Detalles Bibliográficos
Autores principales: Zellner, Elisabeth, Herrmann, Thomas, Schulz, Carsten, Grummt, Friedrich
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175324/
https://www.ncbi.nlm.nih.gov/pubmed/17916579
http://dx.doi.org/10.1093/nar/gkm555