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Probing the structural hierarchy and energy landscape of an RNA T-loop hairpin

The T-loop motif is an important recurrent RNA structural building block consisting of a U-turn sub-motif and a UA trans Watson–Crick/Hoogsteen base pair. In the presence of a hairpin stem, the UA non-canonical base pair becomes part of the UA-handle motif. To probe the hierarchical organization and...

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Detalles Bibliográficos
Autores principales: Zhuang, Zhuoyun, Jaeger, Luc, Shea, Joan-Emma
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175325/
https://www.ncbi.nlm.nih.gov/pubmed/17940098
http://dx.doi.org/10.1093/nar/gkm719