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Trans-lesion synthesis and RNaseH activity by reverse transcriptases on a true abasic RNA template
While much is known about abasic DNA, the biological impact of abasic RNA is largely unexplored. To test the mutagenic potential of this RNA lesion in the context of retroviruses, we synthesized a 31-mer oligoribonucleotide containing an abasic (rAS) site and used it as a template for studying DNA p...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175328/ https://www.ncbi.nlm.nih.gov/pubmed/17932068 http://dx.doi.org/10.1093/nar/gkm767 |