Targeted inhibition of the hepatitis C internal ribosomal entry site genomic RNA with oligonucleotide conjugates

Hepatitis C is a major public health concern, with an estimated 170 million people infected worldwide and an urgent need for new drug development. An attractive therapeutic approach is to prevent the ‘cap-independent’ translation initiation of the viral proteins by interfering with both the structur...

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Detalles Bibliográficos
Autores principales: Guerniou, Valérie, Gillet, Reynald, Berrée, Fabienne, Carboni, Bertrand, Felden, Brice
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175329/
https://www.ncbi.nlm.nih.gov/pubmed/17921501
http://dx.doi.org/10.1093/nar/gkm770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175329/
https://www.ncbi.nlm.nih.gov/pubmed/17921501
http://dx.doi.org/10.1093/nar/gkm770

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