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DNA multiplex hybridization on microarrays and thermodynamic stability in solution: a direct comparison

Hybridization intensities of 30 distinct short duplex DNAs measured on spotted microarrays, were directly compared with thermodynamic stabilities measured in solution. DNA sequences were designed to promote formation of perfect match, or hybrid duplexes containing tandem mismatches. Thermodynamic pa...

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Detalles Bibliográficos
Autores principales: Fish, Daniel J., Horne, M. Todd, Brewood, Greg P., Goodarzi, Jim P., Alemayehu, Saba, Bhandiwad, Ashwini, Searles, Robert P., Benight, Albert S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175334/
https://www.ncbi.nlm.nih.gov/pubmed/17947320
http://dx.doi.org/10.1093/nar/gkm865