Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1

Oxidative stress activates the transcription factor NRF2, which in turn binds cis-acting antioxidant response element (ARE) enhancers and induces expression of protective antioxidant genes. In contrast, the transcriptional repressor BACH1 binds ARE-like enhancers in cells naïve to oxidative stress a...

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Detalles Bibliográficos
Autores principales: Reichard, John F., Motz, Gregory T., Puga, Alvaro
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175339/
https://www.ncbi.nlm.nih.gov/pubmed/17942419
http://dx.doi.org/10.1093/nar/gkm638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175339/
https://www.ncbi.nlm.nih.gov/pubmed/17942419
http://dx.doi.org/10.1093/nar/gkm638

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