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Thermodynamics of DNA target site recognition by homing endonucleases

The thermodynamic profiles of target site recognition have been surveyed for homing endonucleases from various structural families. Similar to DNA-binding proteins that recognize shorter target sites, homing endonucleases display a narrow range of binding free energies and affinities, mediated by st...

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Detalles Bibliográficos
Autores principales: Eastberg, Jennifer H., Smith, Audrey McConnell, Zhao, Lei, Ashworth, Justin, Shen, Betty W., Stoddard, Barry L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175346/
https://www.ncbi.nlm.nih.gov/pubmed/17947319
http://dx.doi.org/10.1093/nar/gkm867