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MyoD uses overlapping but distinct elements to bind E-box and tetraplex structures of regulatory sequences of muscle-specific genes

Muscle differentiation and expression of muscle-specific proteins are initiated by the binding of heterodimers of the transcription factor MyoD with E2A proteins to E-box motif d(CANNTG) in promoters or enhancers of muscle-specific genes. MyoD homodimers, however, form tighter complexes with tetrapl...

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Detalles Bibliográficos
Autores principales: Shklover, Jeny, Etzioni, Shulamit, Weisman-Shomer, Pnina, Yafe, Anat, Bengal, Eyal, Fry, Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175354/
https://www.ncbi.nlm.nih.gov/pubmed/17942416
http://dx.doi.org/10.1093/nar/gkm746