In vivo assembling of bacterial ribosomal protein L11 into yeast ribosomes makes the particles sensitive to the prokaryotic specific antibiotic thiostrepton

Eukaryotic ribosomal stalk protein L12 and its bacterial orthologue L11 play a central role on ribosomal conformational changes during translocation. Deletion of the two genes encoding L12 in Saccharomyces cerevisiae resulted in a very slow-growth phenotype. Gene RPL12B, but not the RPL12A, cloned i...

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Detalles Bibliográficos
Autores principales: García-Marcos, Alberto, Morreale, Antonio, Guarinos, Esther, Briones, Elisa, Remacha, Miguel, Ortiz, Angel R., Ballesta, Juan P. G.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175356/
https://www.ncbi.nlm.nih.gov/pubmed/17940088
http://dx.doi.org/10.1093/nar/gkm773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175356/
https://www.ncbi.nlm.nih.gov/pubmed/17940088
http://dx.doi.org/10.1093/nar/gkm773

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