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A ligation assay for multiplex analysis of CpG methylation using bisulfite-treated DNA
Aberrant methylation of promoter CpG islands is causally linked with a number of inherited syndromes and most sporadic cancers, and may provide valuable diagnostic and prognostic biomarkers. In this report, we describe an approach to simultaneous analysis of multiple CpG islands, where methylation-s...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175362/ https://www.ncbi.nlm.nih.gov/pubmed/17998253 http://dx.doi.org/10.1093/nar/gkm984 |