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Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

BACKGROUND: Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blood mononuclear cells and are the primary type 1 interferon (IFN), producing cells, secreting high levels of IFN in response to viral infections. Plasmacytoid dendritic cells express predominantly TLRs 7 &...

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Detalles Bibliográficos
Autores principales: Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, Nikolsky, Yuri
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175514/
https://www.ncbi.nlm.nih.gov/pubmed/17935622
http://dx.doi.org/10.1186/1471-2172-8-26