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Wee1 kinase alters cyclin E/Cdk2 and promotes apoptosis during the early embryonic development of Xenopus laevis

BACKGROUND: The cell cycles of the Xenopus laevis embryo undergo extensive remodeling beginning at the midblastula transition (MBT) of early development. Cell divisions 2–12 consist of rapid cleavages without gap phases or cell cycle checkpoints. Some remodeling events depend upon a critical nucleo-...

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Detalles Bibliográficos
Autores principales: Wroble, Brian N, Finkielstein, Carla V, Sible, Jill C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176066/
https://www.ncbi.nlm.nih.gov/pubmed/17961226
http://dx.doi.org/10.1186/1471-213X-7-119