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Hepatoma derived growth factor binds DNA through the N-terminal PWWP domain
BACKGROUND: Hepatoma Derived Growth Factor (HDGF) is a nuclear protein with nuclear targeting required for mitogenic activity. Recently we demonstrated that HDGF is a transcriptional repressor, but whether HDGF binds DNA, the specificity of DNA binding and what protein domain is required are still u...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176068/ https://www.ncbi.nlm.nih.gov/pubmed/17974029 http://dx.doi.org/10.1186/1471-2199-8-101 |