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Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays

BACKGROUND: High-density oligonucleotide arrays are widely used for analysis of genome-wide expression and genetic variation. Affymetrix GeneChips – common high-density oligonucleotide arrays – contain perfect match (PM) and mismatch (MM) probes generated by changing a single nucleotide of the PMs,...

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Detalles Bibliográficos
Autores principales: Suzuki, Shingo, Ono, Naoaki, Furusawa, Chikara, Kashiwagi, Akiko, Yomo, Tetsuya
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180184/
https://www.ncbi.nlm.nih.gov/pubmed/17939865
http://dx.doi.org/10.1186/1471-2164-8-373