Determinants of the Nuclear Localization of the Heterodimeric DNA Fragmentation Factor (Icad/Cad)

Programmed cell death or apoptosis leads to the activation of the caspase-activated DNase (CAD), which degrades chromosomal DNA into nucleosomal fragments. Biochemical studies revealed that CAD forms an inactive heterodimer with the inhibitor of caspase-activated DNase (ICAD), or its alternatively s...

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Detalles Bibliográficos
Autores principales: Lechardeur, Delphine, Drzymala, Luke, Sharma, Manu, Zylka, Danuta, Kinach, Robert, Pacia, Joanna, Hicks, Christopher, Usmani, Nawaid, Rommens, Johanna M., Lukacs, Gergely L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180231/
https://www.ncbi.nlm.nih.gov/pubmed/10908575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180231/
https://www.ncbi.nlm.nih.gov/pubmed/10908575

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