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STUDIES IN PORPHYRIA : II. EVIDENCE FOR A DEFICIENCY OF STEROID Δ(4)-5α-REDUCTASE ACTIVITY IN ACUTE INTERMITTENT PORPHYRIA
Patients with the genetic liver disease, acute intermittent porphyria (AIP), have a defect in the reductive transformation of steroid hormones that is manifest by the disproportionate generation of 5β-steroid metabolites from precursor hormones. 5β-steroid metabolites were earlier shown to be potent...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1973
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180579/ https://www.ncbi.nlm.nih.gov/pubmed/4270345 |