STUDIES IN PORPHYRIA : II. EVIDENCE FOR A DEFICIENCY OF STEROID Δ(4)-5α-REDUCTASE ACTIVITY IN ACUTE INTERMITTENT PORPHYRIA

Patients with the genetic liver disease, acute intermittent porphyria (AIP), have a defect in the reductive transformation of steroid hormones that is manifest by the disproportionate generation of 5β-steroid metabolites from precursor hormones. 5β-steroid metabolites were earlier shown to be potent...

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Detalles Bibliográficos
Autores principales: Bradlow, H. Leon, Gillette, Peter N., Gallagher, T. F., Kappas, Attallah
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180579/
https://www.ncbi.nlm.nih.gov/pubmed/4270345

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