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Immune response gene control of determinant selection. I. Intramolecular mapping of the immunogenic sites on insulin recognized by guinea pig T and B cells
T-cell DNA synthesis and T-helper cell function in response to isolated insulin chains and naturally occurring insulin variants was assessed in insulin immune guinea pigs. Two distinct antigenic determinants, recognized by T cells, were defined. One localized in the B chain and the other one constit...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1977
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180714/ https://www.ncbi.nlm.nih.gov/pubmed/95787 |