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B-lymphocytes activation by the Fc region of IgG
Strong stimulation of DNA synthesis (up to 150-fold) and blast transformation can be induced in mouse spleen cells by Fc fragments of human IgG. The mitogenic response is optimal on day 5 of culture and is dependent on the concentration of Fc fragments with a sedimentation rate of 3-5S. Intact IgG i...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1977
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180743/ https://www.ncbi.nlm.nih.gov/pubmed/68990 |