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Enzymes of heme metabolism is the kidney. Regulation by trace metals which do not form heme complexes

The in vivo regulation by metal ions of the enzymes of heme metabolism in kidney-particularly of ALAS, the rate-limiting enzyme in heine formation- was investigated. Ni(2+) and Pt(4+), metals which do not enzymatically form metalloporphyrins, were found to regulate ALAS in kidney as they do in liver...

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Detalles Bibliográficos
Autores principales: Maines, MD, Kappas, A
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180983/
https://www.ncbi.nlm.nih.gov/pubmed/925603