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Spatial requirements between haptenic and carrier determinants for T- dependent antibody responses
To gauge the proximity between cooperating T and B cells required for effective triggering of antibody production, guinea pigs were immunized with bifunctional antigens in which the haptenic and carrier determinants were separated by rigid spacers of varied dimension. These took the form 2,4-dinitro...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1978
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2184992/ https://www.ncbi.nlm.nih.gov/pubmed/81259 |