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Virus-induced diabetes mellitus. XV. Beta cell damage and insulin- dependent hyperglycemia in mice infected with coxsackie virus B4
Coxsackie virus B4 that had been passaged in cultures enriched for pancreatic beta cells produced a diabetes-like syndrome when inoculated into SJL/J mice. The infection resulted in insulitis and destruction of beta cells. Viral antigens were found in beta cells by staining with fluorescein-labeled...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1978
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185018/ https://www.ncbi.nlm.nih.gov/pubmed/212506 |