The Inhibitor of Apoptosis Protein-Binding Domain of Smac Is Not Essential for Its Proapoptotic Activity

Smac/DIABLO, a recently identified inhibitor of apoptosis protein (IAP)-binding protein, is released from the mitochondria during apoptosis and reportedly potentiates apoptosis by relieving the inhibition of IAPs on caspases. We now describe the molecular characterization of Smac β, an alternatively...

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Detalles Bibliográficos
Autores principales: Roberts, Darren L., Merrison, Wendy, MacFarlane, Marion, Cohen, Gerald M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185525/
https://www.ncbi.nlm.nih.gov/pubmed/11285287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185525/
https://www.ncbi.nlm.nih.gov/pubmed/11285287

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