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Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase
Mitosis is controlled by the specific and timely degradation of key regulatory proteins, notably the mitotic cyclins that bind and activate the cyclin-dependent kinases (Cdks). In animal cells, cyclin A is always degraded before cyclin B, but the exact timing and the mechanism underlying this are no...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185531/ https://www.ncbi.nlm.nih.gov/pubmed/11285279 |