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Akt Regulates Cell Survival and Apoptosis at a Postmitochondrial Level

Phosphoinositide 3 kinase/Akt pathway plays an essential role in neuronal survival. However, the cellular mechanisms by which Akt suppresses cell death and protects neurons from apoptosis remain unclear. We previously showed that transient expression of constitutively active Akt inhibits ceramide-in...

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Detalles Bibliográficos
Autores principales: Zhou, Honglin, Li, Xin-Ming, Meinkoth, Judy, Pittman, Randall N.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185587/
https://www.ncbi.nlm.nih.gov/pubmed/11062251