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Mice whose B cells cannot produce the T15 idiotype also lack an antigen- specific helper T cell required for T15 expression
The X-linked CBA/N defect in B cell function precludes an antibody response to phosphorylcholine (PC). Accordingly, (CBA/N X BALB/c)F1 male mice are unresponsive to PC and lack circulating immunoglobulin bearing the T15 idiotype characteristic of BALB/C anti-PC antibody. In contrast, (CBA/N X BALB/c...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1979
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185721/ https://www.ncbi.nlm.nih.gov/pubmed/92522 |