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A gene linked to the Igh-C locus controls the production of rheumatoid factor in the mouse
In certain specific pathogen-free colonies, mice, upon aging, produce autoantibodies (RF) specific for the Fc portion of their IgG. In our colony, 129/Sv mice (H-2bvl; Igh-1a) have 10-20 times higher RF levels than C5BL/6 (h-2b; Igh-1b). In addition, the 129 have mainly IgA anti- IgG2a, and the B6 h...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1981
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186098/ https://www.ncbi.nlm.nih.gov/pubmed/6972988 |