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Distinct TLR- and NLR-Mediated Transcriptional Responses to an Intracellular Pathogen

How the innate immune system tailors specific responses to diverse microbial infections is not well understood. Cells use a limited number of host receptors and signaling pathways to both discriminate among extracellular and intracellular microbes, and also to generate responses commensurate to each...

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Detalles Bibliográficos
Autores principales: Leber, Jess H, Crimmins, Gregory T, Raghavan, Sridharan, Meyer-Morse, Nicole P, Cox, Jeffery S, Portnoy, Daniel A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186359/
https://www.ncbi.nlm.nih.gov/pubmed/18193943
http://dx.doi.org/10.1371/journal.ppat.0040006