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Antigen responsiveness of the mature and generative B cell populations of aged mice
The deficit of humoral immune responsiveness associated with aging was investigated at the level of individual antigen-specific B cells. It was found that mature dinitrophenyl (DNP)-responsive B cells isolated from the spleen of aged mice gave rise to clones of antibody-forming cells that were norma...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1983
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186981/ https://www.ncbi.nlm.nih.gov/pubmed/6187890 |