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Haptens can serve as surrogate transplantation antigens in a manner that demonstrates H-2 restriction of graft rejection
Hapten-immune mice are capable of rejecting syngeneic skin grafts that are derivatized with the relevant hapten, but only if the hapten is applied while the graft is "healing in." This model system was used to demonstrate that the hapten-specific immune effectors responsible for rejection...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1983
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186986/ https://www.ncbi.nlm.nih.gov/pubmed/6339670 |