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Carboxylic ionophores enhance the cytotoxic potency of ligand- and antibody-delivered ricin A chain
The highly selective cytotoxicity of site-directed ricin A chain conjugates can be potentiated by membrane-active carboxylic ionophores. The combined use of the two agents results in much faster inactivation of ribosomes and subsequent cell death and lysis. The potency of A chain cytotoxins is corre...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1984
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2187464/ https://www.ncbi.nlm.nih.gov/pubmed/6090575 |